Amino acids are molecules that combine to form proteins. Amino acids and proteins are the building blocks of life. When proteins are digested or broken down, amino acids are left. The human body uses amino acids to make proteins to help the body: Break down food.

Tryptophan is an essential amino acid that cannot be produced by the human body and must be obtained through your diet, primarily from animal or plant based protein sources. Tryptophan is synthesized into serotonin, melatonin .

Nutrients are chemical compounds in food that are used by the body to function properly and maintain health. Examples include proteins, fats, carbohydrates, vitamins, and minerals.

Psilocybin Mushrooms are rich sources of essential amino acids, proteins, minerals, vitamins and carbohydrates.

The metabolization of trytophan is associated with reducing inflammation, regulation of energy and behavior modulation.

Tryptophan is the precursor of key neurochemicals such as serotonin and melatonin, which help the body manage sleep, control moods, and anxiety. Individuals with autism metabolize

L-tryptophan at a decreased rate.

Autism spectrum disorder (ASD) is a range of neurodevelopmental conditions that affect communication and social behavior. Besides social “deficits”, systemic inflammation, gastrointestinal immune-related problems, and changes in the gut microbiota composition are characteristic for people with autism.

Animal models showed that these characteristics can induce autistic associated behavior, suggesting an intimate relationship between the microbiota, GUT immune system and the brain in autism.

Fecal Microbiome Transplantation from Children with Autism Spectrum Disorder Modulates Tryptophan and Serotonergic Synapse Metabolism and Induces Altered Behaviors in Germ-Free Mice

Authors: Lu Xiao, Junyan Yan, Ting Yang, Jiang Zhu, Tingyu Li, Hong Wei weihong63528@163.com, Jie Chen https://orcid.org/0000-0001-5142-4338 jchen010@hospital.cqmu.edu.cnAUTHORS INFO & AFFILIATIONS

DOI

:

https://doi.org/10.1128/mSystems.01343-20

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Other studies

Boccuto, L., Chen, CF., Pittman, A.R. et al. Decreased tryptophan metabolism in patients with autism spectrum disorders. Molecular Autism 4, 16 (2013). https://doi.org/10.1186/2040-2392-4-16

*Higazi, A.M., Kamel, H.M., Abdel-Naeem, E.A. et al. Expression analysis of selected genes involved in tryptophan metabolic pathways in Egyptian children with Autism Spectrum Disorder and learning disabilities. Sci Rep 11, 6931 (2021). https://doi.org/10.1038/s41598-021-86162-w

*The Gut-Immune-Brain Axis in Autism Spectrum Disorders; A Focus on Amino Acid

Joris H. J. van Sadelhoff1,Paula Perez Pardo, Jiangbo Wu..

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